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Updated: Sep 29, 2026

An Immature Murine Model of Reversible Unilateral Ureteral Obstruction
Published on: April 4, 2025
Surgery of pelviureteric obstruction in the first year of life
Insights
Congenital pelviureteric obstruction surgery in infants under 1 year old shows good outcomes. Most infants undergoing pyeloplasty experienced satisfactory recovery, with renal nuclide scans proving effective for follow-up.
Area of Science:
- Pediatric Surgery
- Urology
- Nephrology
Background:
- Congenital pelviureteric obstruction is a significant cause of hydronephrosis in infants.
- Early diagnosis and intervention are crucial for preserving renal function in pediatric patients.
- Understanding surgical outcomes in very young children is essential for optimizing treatment strategies.
Abstract:
Twenty-nine out of 108 patients (26%) were under 1 year of age at the time of surgery for congenital pelviureteric obstruction. The clinical features and diagnosis, management, follow-up and results in these patients are reviewed. Clinical presentation was usually with an abdominal mass or urinary infection but an increasing number of cases were diagnosed after maternal ultrasonography had shown hydronephrosis. Ultrasonography, together with renal nuclide scan, were considered to be the most appropriate imaging modalities to define anatomy, determine function and document obstruction. Pyeloplasty was carried out successfully in 28 patients (two bilateral) and one patient had a nephrectomy. Sixteen pyeloplasties were managed by a nephrostomy (with or without a stent), the tubes usually being removed 10-12 days postoperatively. Fourteen pyeloplasties were managed by a wound drain only but one required a secondary nephrostomy although eventual recovery was satisfactory. Renal nuclide scan was found to be the most appropriate follow-up test and the overall results of surgery were satisfactory.
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