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Updated: Jun 20, 2025

Author Spotlight: An Efficient and Robust Software for Automated Fusion of Multiple Preclinical Imaging Modalities
Published on: October 27, 2023
US & MR/CT Image Fusion with Markerless Skin Registration: A Proof of Concept
Martina Paccini1, Giacomo Paschina2, Stefano De Beni2
1CNR-IMATI 'E. Magenes', via de Marini, 6, Genova, Italy. martina.paccini@ge.imati.cnr.it.
Abstract:
This paper presents an innovative automatic fusion imaging system that combines 3D CT/MR images with real-time ultrasound acquisition. The system eliminates the need for external physical markers and complex training, making image fusion feasible for physicians with different experience levels. The integrated system involves a portable 3D camera for patient-specific surface acquisition, an electromagnetic tracking system, and US components. The fusion algorithm comprises two main parts: skin segmentation and rigid co-registration, both integrated into the US machine. The co-registration aligns the surface extracted from CT/MR images with the 3D surface acquired by the camera, facilitating rapid and effective fusion. Experimental tests in different settings, validate the system's accuracy, computational efficiency, noise robustness, and operator independence.
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