Related Experiment Video
Updated: Jun 20, 2025

Forming, Confining, and Observing Microtubule-Based Active Nematics
Published on: January 13, 2023
Periodic orbits, pair nucleation, and unbinding of active nematic defects on cones
Farzan Vafa1, David R Nelson2, Amin Doostmohammadi3
1Center of Mathematical Sciences and Applications, <a href="https://ror.org/03vek6s52">Harvard University</a>, Cambridge, Massachusetts 02138, USA.
Abstract:
Geometric confinement and topological constraints present promising means of controlling active materials. By combining analytical arguments derived from the Born-Oppenheimer approximation with numerical simulations, we investigate the simultaneous impact of confinement together with curvature singularity by characterizing the dynamics of an active nematic on a cone. Here, the Born-Oppenheimer approximation means that textures can follow defect positions rapidly on the timescales of interest. Upon imposing strong anchoring boundary conditions at the base of a cone, we find a rich phase diagram of multidefect dynamics, including exotic periodic orbits of one or two +1/2 flank defects, depending on activity and nonquantized geometric charge at the cone apex. By characterizing the transitions between these ordered dynamical states, we present detailed understanding of (i) defect unbinding, (ii) defect absorption, and (iii) defect pair nucleation at the apex. Numerical simulations confirm theoretical predictions of not only the nature of the circular orbits but also defect unbinding from the apex.
Related Concept Videos
¹H NMR of Conformationally Flexible Molecules: Temporal Resolution
Atomic Nuclei: Nuclear Relaxation Processes
Spin–Spin Coupling: Two-Bond Coupling (Geminal Coupling)
The central atom need not be NMR-active because its electrons are affected by the electron polarization of the spin-active atoms. However, spin information is transmitted less effectively than in one-bond coupling, and 2J values are usually weaker than 1J values. The energy of...
Frost Circles for Different Conjugated Systems
Forces Acting on Chromosomes
Microtubules and motor proteins exert two types of forces on...
Newman Projections
The organic molecules rotate across the single bonds leading to numerous temporary three-dimensional structures of varying energy known as...

