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The initiation of cell-mediated immunity can be observed as early as the third month of fetal growth, with active antibody-mediated immunity following approximately one month later.
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Sublingual Immunotherapy as an Alternative to Induce Protection Against Acute Respiratory Infections
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A practical focus on peanut oral immunotherapy.

Tricia Lee1,2, Codi Horton1, Chelsea Leef1

  • 1From the Children's Healthcare of Atlanta, Atlanta, Georgia; and.

Journal of Food Allergy
|July 18, 2024
PubMed
Summary
This summary is machine-generated.

A new era of active treatment for food allergy is here, with oral immunotherapy (OIT) offering new options for peanut allergy patients. This review covers FDA-approved OIT and other products, guiding allergy practice.

Keywords:
1 peanut OIT2 Palforzia3 REMS4 AR101567

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Area of Science:

  • Allergy and Immunology
  • Clinical Medicine

Background:

  • Oral immunotherapy (OIT) represents a significant advancement in food allergy treatment.
  • Peanut allergy affects a growing number of individuals, necessitating effective management strategies.

Purpose of the Study:

  • To review the current literature on oral immunotherapy for peanut allergy.
  • To provide practical guidance on utilizing U.S. Food and Drug Administration (FDA)-approved OIT and commercially available products.

Main Methods:

  • Literature review of clinical research on peanut OIT.
  • Analysis of practical considerations for implementing OIT in clinical settings.

Main Results:

  • Oral immunotherapy is emerging as a viable active treatment for peanut allergy.
  • Guidance is provided for the use of both FDA-approved and other available OIT products.

Conclusions:

  • The availability of OIT marks a new phase in active food allergy treatment.
  • This review aims to inform allergy practice regarding the use of peanut OIT.