Related Experiment Video
Updated: Jun 20, 2025

Basophil Activation Test for Allergy Diagnosis
Published on: May 31, 2021
Considerations for a shared decision-making conversation when initiating food oral immunotherapy
Matthew Greenhawt1, David Fleischer1
1From the Food Challenge and Research Unit, Children's Hospital of Colorado, Section of Allergy and Immunology, University of Colorado School of Medicine, Aurora, Colorado.
Oral immunotherapy (OIT) offers potential desensitization for food allergies but carries risks like reactions and uncertain outcomes. Shared decision-making is crucial for informed consent regarding OIT risks and benefits.
Area of Science:
- Allergy and Immunology
- Clinical Medicine
Background:
- Food allergy affects many, with oral immunotherapy (OIT) emerging as a treatment option.
- OIT aims to desensitize patients, potentially reducing reaction severity, but is not a cure.
Purpose of the Study:
- To outline key considerations for shared decision-making before initiating OIT.
- To facilitate informed consent by discussing OIT risks and benefits with patients and families.
Main Methods:
- Review of OIT benefits, risks, and decision-making processes.
- Emphasis on shared decision-making involving patients, families, and clinicians.
Main Results:
- OIT can shift reaction thresholds and decrease severity but has risks including anaphylaxis and eosinophilic esophagitis.
- Long-term outcomes of OIT remain uncertain, posing logistical challenges.
Conclusions:
- The decision to pursue OIT is complex and requires thorough discussion of all factors.
- Shared decision-making empowers patients and families to make informed choices aligned with their values and preferences.
Related Concept Videos
Enteral Nutrition II: Nasointestinal and Gastrostomy Feeding
Nasointestinal Feeding
Nasointestinal feeding involves placing a tube...
SBAR II: Application of SBAR
SBAR Report from a Nurse to a Health Care Provider
S: "Hello, Dr. Smith. This is Jane, RN, from the Med Surg unit. I am calling to tell you about Ms. White in Room 210, who is experiencing increased pain and redness at her incision site. Her recent...
Role of Communication in the Nursing Process II: Planning and Implementation
Tumor Immunotherapy
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
Nursing Ethical Principles II
Consider the following scenario, which illustrates how these principles are applied in the care of Mr. John, a fifty-year-old teacher diagnosed with metastatic liver cancer.
Initially, Mr. John's...

