Related Experiment Video
Updated: Jun 20, 2025
Bio-energetics Investigation of Candida albicans Using Real-time Extracellular Flux Analysis
Published on: March 19, 2019
Recurrent Fungemia Due to Candida auris
Emma M Griffith1, Christopher Marsalisi1, Jorge Verdecia2
1Internal Medicine, University of Florida College of Medicine-Jacksonville, Jacksonville, USA.
Abstract:
We present a case of recurrent multidrug-resistant Candida auris (C. auris) in a patient who required multiple hospitalizations. The patient's case was complicated by interval admissions to the intensive care unit for septic and hypovolemic shock for 12 months to manage C. auris fungemia. Despite adequate isolation precautions and appropriate antifungal treatment, this case demonstrates the profound implications of this emerging pathogen, specifically regarding invasive infections. Moreover, C. auris is rapidly becoming known as a multidrug-resistant organism, which limits treatment options and thus contributes to high mortality.
Insights
Recurrent multidrug-resistant Candida auris (C. auris) infections pose significant challenges. This case highlights the difficulties in managing invasive C. auris, emphasizing its resistance and high mortality risk.
Area of Science:
- Infectious Diseases
- Mycology
- Critical Care Medicine
Background:
- Candida auris (C. auris) is an emerging multidrug-resistant fungal pathogen.
- Invasive C. auris infections are associated with high morbidity and mortality.
- Management of C. auris requires careful consideration of limited treatment options.
Observation:
- A case of recurrent, multidrug-resistant C. auris fungemia is presented.
- The patient experienced multiple hospitalizations and intensive care unit admissions over 12 months.
- Septic and hypovolemic shock complicated the management of C. auris fungemia.
Findings:
- Despite isolation and antifungal therapy, C. auris fungemia recurred.
- The case underscores the challenges posed by multidrug-resistant C. auris.
- Invasive C. auris infections demonstrate profound clinical implications.
Implications:
- This case highlights the need for enhanced surveillance and infection control for C. auris.
- Limited treatment options for multidrug-resistant C. auris contribute to poor outcomes.
- Further research is needed to develop effective therapeutic strategies against C. auris.
