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Li-Fraumeni Syndrome: Imaging Features and Guidelines

Babina Gosangi1, Irene Dixe de Oliveira Santo1, Abhishek Keraliya1

  • 1From the Department of Radiology and Biomedical Imaging (B.G., I.D.d.O.S., A.N.R., A.S.B.), Section of Interventional Radiology (Y.W.), Yale School of Medicine, 333 Cedar Street, PO Box 208042, Rm TE-2, New Haven, CT 06520; Department of Radiology, Brigham and Women's Hospital, Boston, Mass (A. Keraliya); Magnus Hospital, Hyderabad, India (D.I.); Department of Radiology, Lahey Hospital and Medical Care Center, Burlington, Mass (R.T.); and Department of Radiology, Mayo University, Rochester, Minn (A. Khandelwal).

Radiographics : a Review Publication of the Radiological Society of North America, Inc
|July 18, 2024
PubMed
Summary

Li-Fraumeni syndrome (LFS) is a genetic condition increasing cancer risk due to TP53 gene mutations. Early cancer detection through whole-body MRI screening is crucial for managing LFS patients.

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