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Potential medication-related problems in noninstitutionalized elderly.

L A Shimp, F J Ascione, H M Glazer

    Drug Intelligence & Clinical Pharmacy
    |October 1, 1985
    PubMed
    Summary
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    Elderly patients with multiple chronic illnesses and medications face numerous medication-related problems, including toxicity and prescribing issues. A comprehensive drug therapy review is crucial for identifying and preventing these issues in polypharmacy patients.

    Area of Science:

    • Gerontology
    • Clinical Pharmacy
    • Pharmacology

    Background:

    • Polypharmacy is common in elderly patients with multiple chronic illnesses.
    • Medication-related problems pose significant risks to patient safety and health outcomes.
    • Comprehensive drug therapy reviews are essential for managing complex medication regimens.

    Purpose of the Study:

    • To examine the extent and types of potential medication-related problems in elderly patients using multiple medications.
    • To identify predictors of medication-related problems in this population.
    • To evaluate the utility of a drug therapy review in identifying and preventing these problems.

    Main Methods:

    • A thorough review of drug therapy was conducted for 53 elderly patients.
    • Patients averaged five chronic illnesses and used a mean of 11 drugs.

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  • Potential medication-related problems were categorized into drug toxicity, physician prescribing, and patient medication behaviors.

    • Main Results:

    • An average of 11 specific potential medication-related problems were identified per patient.
    • The number of prescription medications was the strongest predictor of total problems.
    • Problems encompassed drug toxicity, physician prescribing errors, and patient medication adherence issues.

    Conclusions:

    • Elderly patients with multiple chronic conditions and polypharmacy are at high risk for medication-related problems.
    • A systematic drug therapy review is effective in identifying a high number of potential medication-related problems.
    • This review approach can aid healthcare professionals in preventing medication-related issues in patients with complex medication needs.