Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Role of Hippocampus in Memory01:19

Role of Hippocampus in Memory

207
The hippocampus, a critical brain structure, plays an essential role in memory processing, particularly in the formation and retrieval of memory. This small, seahorse-shaped region is located within the medial temporal lobe, with one hippocampus in each brain hemisphere. Experimental studies involving lesions in the hippocampi of rats have demonstrated significant impairments in tasks such as object recognition and maze navigation, indicating the hippocampus involvement in both recognition and...
207
Association Areas of the Cortex01:21

Association Areas of the Cortex

5.2K
Association areas are regions of the cerebral cortex that do not have a specific sensory or motor function. Instead, they integrate and interpret information from various sources to enable higher cognitive processes such as memory, learning, and decision-making. Some key association areas include the following:
Prefrontal Association Area: This area is located in the frontal lobe and is involved in planning, decision-making, and moderating social behavior. It connects with primary motor areas,...
5.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

REM sleep prefrontal ripple chains mediate distinct cortical-hippocampal reactivation patterns compared to NREM ripples.

bioRxiv : the preprint server for biology·2025
Same author

A Novel Rat Spatial Inference Task Reveals Rapid Deduction of Transitive Relationships Using Schemas and Deliberation.

bioRxiv : the preprint server for biology·2025
Same author

Adapt-A-Maze: An Open-Source Adaptable and Automated Rodent Behavior Maze System.

eNeuro·2025
Same author

Intrinsic dynamics of randomly clustered networks generate place fields and preplay of novel environments.

eLife·2024
Same author

Ventral tegmental area dopamine neural activity switches simultaneously with rule representations in the prefrontal cortex and hippocampus.

bioRxiv : the preprint server for biology·2024
Same author

Cortical ripples mediate top-down suppression of hippocampal reactivation during sleep memory consolidation.

bioRxiv : the preprint server for biology·2024
Same journal

A human-specific genetic modifier reconfigures large-scale cortical network dynamics underlying behavioral performance.

bioRxiv : the preprint server for biology·2026
Same journal

<i>Staphylococcus aureus</i> uses a eukaryotic-like uridyltransferase to make UDP-GlcNAc for cell wall synthesis.

bioRxiv : the preprint server for biology·2026
Same journal

Dynamic redistribution of eIF4F controls cap-dependent translation initiation.

bioRxiv : the preprint server for biology·2026
Same journal

When does additional information improve accuracy of RNA secondary structure prediction?

bioRxiv : the preprint server for biology·2026
Same journal

Normative brain-state trajectories reveal deviation from healthy aging in Alzheimer's disease.

bioRxiv : the preprint server for biology·2026
Same journal

Noradrenergic infraslow rhythm during sleep is the critical link between heart-rate dynamics and memory consolidation.

bioRxiv : the preprint server for biology·2026
See all related articles

Related Experiment Video

Updated: Jun 20, 2025

Author Spotlight: Investigating the Effects of Mind-Body-Movement Practices on Brain Function
06:17

Author Spotlight: Investigating the Effects of Mind-Body-Movement Practices on Brain Function

Published on: January 26, 2024

1.9K

Hippocampal-prefrontal communication subspaces align with behavioral and network patterns in a spatial memory task.

Ryan A Young, Justin D Shin, Ziyi Guo

    Biorxiv : the Preprint Server for Biology
    |July 19, 2024
    PubMed
    Summary
    This summary is machine-generated.

    Brain oscillations and speed dynamically shape neural communication subspaces between the hippocampus and prefrontal cortex during memory tasks. These shared neural patterns, not local activity, drive behavior, revealing a novel interplay between brain rhythms and cognition.

    More Related Videos

    A Video Demonstration of Preserved Piloting by Scent Tracking but Impaired Dead Reckoning After Fimbria-Fornix Lesions in the Rat
    08:37

    A Video Demonstration of Preserved Piloting by Scent Tracking but Impaired Dead Reckoning After Fimbria-Fornix Lesions in the Rat

    Published on: April 24, 2009

    11.8K
    Modeling the Functional Network for Spatial Navigation in the Human Brain
    05:55

    Modeling the Functional Network for Spatial Navigation in the Human Brain

    Published on: October 13, 2023

    1.0K

    Related Experiment Videos

    Last Updated: Jun 20, 2025

    Author Spotlight: Investigating the Effects of Mind-Body-Movement Practices on Brain Function
    06:17

    Author Spotlight: Investigating the Effects of Mind-Body-Movement Practices on Brain Function

    Published on: January 26, 2024

    1.9K
    A Video Demonstration of Preserved Piloting by Scent Tracking but Impaired Dead Reckoning After Fimbria-Fornix Lesions in the Rat
    08:37

    A Video Demonstration of Preserved Piloting by Scent Tracking but Impaired Dead Reckoning After Fimbria-Fornix Lesions in the Rat

    Published on: April 24, 2009

    11.8K
    Modeling the Functional Network for Spatial Navigation in the Human Brain
    05:55

    Modeling the Functional Network for Spatial Navigation in the Human Brain

    Published on: October 13, 2023

    1.0K

    Area of Science:

    • Neuroscience
    • Cognitive Neuroscience
    • Systems Neuroscience

    Background:

    • Rhythmic network states are theorized to facilitate inter-regional brain communication.
    • The influence of oscillations on communication subspaces and their behavioral impact is not well understood.

    Purpose of the Study:

    • To investigate how neural oscillations and speed modulate communication subspaces between the hippocampus (CA1) and prefrontal cortex (PFC).
    • To determine if shared neural activity subspaces, rather than local activity, predict task behavior.

    Main Methods:

    • Simultaneous ensemble recordings from hippocampal CA1 and PFC in rats performing a spatial memory task.
    • Analysis of low-dimensional neural activity patterns and their relationship to behavior.
    • Utilized manifold techniques to visualize communication geometry.

    Main Results:

    • Task behavior aligned best with low-dimensional, shared CA1-PFC subspaces.
    • Network oscillations (specifically theta power) and speed modulated the communication subspace structure and performance.
    • Theta coherence was a weaker predictor of shared activity compared to theta power.
    • Visualizations revealed ring-like structures in shared CA1-PFC communication geometry.

    Conclusions:

    • Memory-guided behaviors are driven by shared CA1-PFC neural interactions.
    • These interactions are dynamically modulated by oscillatory states, particularly theta power.
    • Findings offer a novel perspective on the interplay between neural rhythms and behaviorally relevant communication.