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Skin Diseases and Disorders

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...

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Updated: Jun 20, 2025

Primed Mycobacterial Uveitis PMU as a Model for Post-Infectious Uveitis

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Published on: December 17, 2021

Monkeypox-related ophthalmic disease.

Liang Yi-Ting¹, Huang Chien-Hsien^2,3, Fang Hwa-Hsin¹

¹Department of Ophthalmology, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan.

Taiwan Journal of Ophthalmology

|July 19, 2024

Summary

Monkeypox (Mpox) can cause uncommon eye infections, including severe keratitis. Early treatment is crucial for managing Mpox virus ocular complications and preventing vision loss.

Keywords:

Blepharoconjunctivitis keratitis monkeypox uveitis

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Last Updated: Jun 20, 2025

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Induction of Ocular Surface Inflammation and Collection of Involved Tissues

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Published on: August 4, 2022

Area of Science:

Ophthalmology
Infectious Diseases
Virology

Background:

Monkeypox (Mpox) virus, causing acute febrile rash illness, has seen a global outbreak since mid-2022.
Ocular involvement in Mpox is rare, typically presenting as external or ocular surface lesions.

Observation:

A case study details a man with unilateral blepharoconjunctivitis and preseptal cellulitis preceding skin symptoms by six days.
Oropharyngeal and skin lesion samples confirmed Mpox virus via PCR.
Ocular Mpox recurrence manifested as punctate epithelial keratitis, progressing to dendritic ulceration despite initial tecovirimat treatment.

Findings:

The corneal lesion tested positive for Mpox virus, indicating direct viral involvement.
Deterioration of keratitis and anterior chamber inflammation necessitated additional treatment with low-dose steroids and ganciclovir.
The patient ultimately recovered from the corneal lesion, though a scar remained.

Implications:

This case highlights the potential for severe and progressive ocular Mpox infections.
It underscores the importance of considering Mpox in patients with unusual ocular presentations, especially during outbreaks.
The case demonstrates the complex management required for Mpox keratitis, sometimes involving combination therapy.