Related Experiment Video
Updated: Jun 20, 2025
In Vivo Quantification of Hip Arthrokinematics during Dynamic Weight-bearing Activities using Dual Fluoroscopy
Published on: July 2, 2021
An Atypical Cause of a Child Limp: A Gorham-Stout Disease with a Vanishing Hip
Hanene Lassoued Ferjani1, Yasmin Makhlouf1, Dorra Ben Nessib1
1Departamento de Reumatologia, Kassab Orthopedics Institute, Ksar Saïd, Tunisia.
Insights
Gorham-Stout disease (GSD) is a rare, destructive bone disorder affecting young people. This report details a rare pediatric case of GSD impacting the hip and iliac crest, highlighting the need for further research.
Area of Science:
- Orthopedics
- Vascular Biology
- Pediatric Rare Diseases
Background:
- Gorham-Stout disease (GSD) is a rare, debilitating bone disorder.
- It involves abnormal proliferation of vascular endothelial cells leading to bone destruction.
- GSD commonly affects children and young adults, causing significant morbidity and mortality.
Purpose of the Study:
- To report a rare case of Gorham-Stout disease in a pediatric patient.
- To describe the location and presentation of GSD in the hip and iliac crest.
- To contribute to the limited literature on GSD management and characteristics.
Main Methods:
- Case report of a pediatric patient diagnosed with Gorham-Stout disease.
- Clinical and radiological assessment of the affected hip and iliac crest region.
- Review of existing literature on Gorham-Stout disease presentation and management.
Main Results:
- A rare case of Gorham-Stout disease was identified in a child.
- The disease affected the hip and iliac crest bones.
- The case highlights the varied presentation of GSD in pediatric populations.
Conclusions:
- Gorham-Stout disease is a rare condition with no established treatment.
- Pediatric GSD can present in unusual locations like the hip and iliac crest.
- Further studies are needed to understand GSD pathogenesis and develop effective treatments.
Abstract:
Gorham-Stout disease (GSD) is a rare bone disease characterized by an abnormal proliferation of endothelial-lined vessels and destruction of the affected bone. As it affects commonly children and young adults, it is associated with significant morbidity and mortality. To date, there is no established treatment strategy for GSD. We report through this observation a rare case of GSD in a child located in the hip and the iliac crest.
