Related Experiment Video
Updated: Jun 20, 2025

09:49
Surgical Closure of Equine Abdomen, Prevention, and Management of Incisional Complications
Published on: May 10, 2024
723
Closed Incision Negative-Pressure Therapy on Free Flap Donor Sites: A Meta-analysis of Postoperative Outcomes
Paulina B Le1, O Parker Martinez2, Tarik Mujadzic1
1From Division of Plastic and Reconstructive Surgery at Prisma Health-Midlands/University of South Carolina School of Medicine, Columbia, S.C.
Plastic and Reconstructive Surgery. Global Open
|July 19, 2024
Summary
Closed incision negative-pressure therapy (ciNPT) significantly reduces wound dehiscence at free flap donor sites. This therapy also shows a trend toward lowering other complications like infection and seroma compared to traditional dressings.
Area of Science:
- Plastic Surgery
- Wound Healing
- Surgical Site Management
Background:
- Closed incision negative-pressure therapy (ciNPT) is increasingly used for surgical sites.
- Limited literature exists on ciNPT's benefits for free tissue transfer donor sites.
- This review compares ciNPT with conventional dressings for donor site complications.
Purpose of the Study:
- To compare the effectiveness of ciNPT and conventional dressings.
- To evaluate the reduction of donor site morbidity after free tissue transfer.
Main Methods:
- Systematic review of PubMed and Ovid (MEDLINE).
- Search terms included flap, donor, negative pressure, and vacuum.
- Bibliographies of selected articles were also searched.
Main Results:
- 12 studies with 1074 donor sites were analyzed.
- ciNPT showed a significantly lower incidence of wound dehiscence (OR: 0.37).
- Infection, seroma, hematoma, and skin necrosis rates were lower with ciNPT, but not statistically significant.
Conclusions:
- ciNPT significantly reduces wound dehiscence at free flap donor sites.
- ciNPT use appears to lower overall wound complication rates, including seroma, hematoma, skin necrosis, and infection.

