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PPCRKB: a risk factor knowledge base of postoperative pulmonary complications.
Jianchao Duan1,2,3,4, Peiyi Li1,2,3, Aibin Shao5
1Department of Anesthesiology, West China Hospital, Sichuan University, No. 37th, Guoxue Alley, Wuhou District, Chengdu, Sichuan 610041, China.
View abstract on PubMed
A new online knowledge platform, the Postoperative Pulmonary Complications Risk Factor Knowledge Base (PPCRKB), has been developed. It categorizes 915 risk factors to aid in preventing and managing postoperative pulmonary complications.
Area of Science:
- Medical Informatics
- Pulmonology
- Surgical Research
Background:
- Postoperative pulmonary complications (PPCs) are heterogeneous disorders with diverse risk factors, leading to increased costs, prolonged hospital stays, and mortality.
- Existing research on PPCs lacks a unified knowledge base for integrating and visualizing diverse risk factors.
- A comprehensive resource is needed to support the development of individualized prevention and management strategies for PPCs.
Purpose of the Study:
- To develop an online knowledge platform, the Postoperative Pulmonary Complications Risk Factor Knowledge Base (PPCRKB).
- To categorize and present risk and protective factors associated with PPCs.
- To facilitate the creation of tailored prevention and management strategies for PPCs.
Main Methods:
- Development of a novel web-based knowledge base (PPCRKB).
- Inclusion of 2673 entries detailing 915 risk factors linked to PPCs.
- Categorization of risk factors into 11 distinct groups (e.g., habit and behavior, surgical, anesthetic, clinical status, genetic).
Main Results:
- The PPCRKB integrates a comprehensive list of potential risk factors for PPCs.
- It categorizes 915 risk factors into 11 groups, providing a structured overview.
- The platform includes both quantitative and qualitative data, enhancing research insights.
Conclusions:
- The PPCRKB offers a valuable resource for PPC research by consolidating diverse risk factors.
- It provides a comprehensive perspective for clinicians and researchers on PPC-related factors.
- The platform supports the advancement of individualized prevention and management strategies for PPCs.


