Application of 3D printing on the design and development of pharmaceutical oral dosage forms
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View abstract on PubMed
Summary
This summary is machine-generated.3D printing offers precise control for personalized pharmaceutical dosage forms, tailoring drug release profiles. This review explores fused deposition modeling and other 3D printing technologies for oral drug delivery advancements.
Area Of Science
- Pharmaceutical Sciences
- Materials Science
- Biotechnology
Background
- 3D printing technologies provide exceptional control over material distribution in pharmaceutical dosage forms.
- This control is crucial for developing personalized medicines and tailoring drug release.
- Fused Deposition Modeling (FDM) is a primary focus, but other 3D printing methods are emerging in pharmaceutical research.
Purpose Of The Study
- To review the advantages and limitations of various 3D printing technologies in pharmaceutical oral dosage form design.
- To highlight recent advancements in 3D printed dosage forms developed in 2022-2023.
- To emphasize the impact of 3D printing on drug release profiles and biopharmaceutical behavior.
Main Methods
- Literature review of 3D printing technologies applied to oral dosage forms.
- Analysis of material selection and design strategies in 3D printed pharmaceuticals.
- Focus on fused deposition modeling (FDM) and emerging 3D printing techniques.
Main Results
- 3D printing enables precise control over drug content and release kinetics.
- Personalized dosage forms with tailored biopharmaceutical properties are achievable.
- Recent studies showcase novel 3D printed oral dosage forms with controlled drug release.
Conclusions
- 3D printing technologies are poised to integrate with current pharmaceutical manufacturing.
- Continued research is expanding the capabilities of 3D printed oral dosage forms.
- Understanding material properties and design is key to optimizing drug release profiles.
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