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Related Experiment Video

Updated: Jun 20, 2025

Developing Neuroimaging Phenotypes of the Default Mode Network in PTSD: Integrating the Resting State, Working Memory, and Structural Connectivity

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Frontoparietal Brain Network Plays a Crucial Role in Working Memory Capacity during Complex Cognitive Task.

Nikita Otstavnov¹, Carlos Nieto-Doval¹, Giulia Galli²

¹Centre for Cognition and Decision making, Institute for Cognitive Neuroscience, Higher School of Economics University, Moscow 101000, Russia.

|July 19, 2024

Summary

Dual-site transcranial direct current stimulation of the frontoparietal network (FPN) enhanced working memory (WM) accuracy and speed. This neurostimulation approach offers a promising method for cognitive enhancement.

Keywords:

frontoparietal network high-definition transcranial direct current stimulation operation span task working memory working memory capacity

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Published on: August 9, 2016

Area of Science:

Neuroscience
Cognitive Psychology
Neuroimaging

Background:

Working memory (WM) capacity is crucial for cognitive functions.
Previous studies on frontoparietal network (FPN) stimulation for WM enhancement yielded inconsistent results.
Optimizing neurostimulation techniques for cognitive enhancement remains an active research area.

Purpose of the Study:

To investigate the efficacy of dual-site high-definition transcranial direct current stimulation (tDCS) in enhancing working memory capacity.
To explore the differential roles of frontal and parietal components of the FPN in working memory.

Main Methods:

Forty-eight participants were randomly assigned to three groups: double stimulation (simultaneous frontal and parietal anodal tDCS), single stimulation (frontal anodal tDCS), or sham stimulation.
Working memory performance was assessed using an operation span task measuring memory accuracy, mathematical accuracy, calculation/memorization time, and recall response time.

Main Results:

The double stimulation group showed significantly improved memory accuracy and reduced calculation time compared to single and sham groups.
Both double and single stimulation groups exhibited decreased recall response time compared to the sham group.
No significant differences in mathematical accuracy were found across the groups.

Conclusions:

Dual-site FPN stimulation effectively enhances working memory capacity.
The findings suggest a functional dissociation within the FPN, with frontal areas involved in retrieval and parietal areas in processing and retention stages of working memory.