Related Experiment Video
Updated: Jun 20, 2025

Author Spotlight: Unveiling the Connection Between Sleep Disorders and Cognitive Symptoms in Depression
Published on: April 26, 2024
Improving Parkinson's Disease Care through Systematic Screening for Depression.
Connie Marras1, Zachary Meyer2, Hongliang Liu3
1The Edmond J. Safra Program in Parkinson's Disease and the Morton and Gloria Shulman Movement Disorders Center, Toronto Western Hospital, Department of Medicine, University of Toronto, Toronto, Ontario, Canada.
Implementing formal depression screening for Parkinson's disease (PD) patients significantly increased detection rates. Tailored clinical processes are essential to overcome implementation barriers and improve patient care.
Area of Science:
- Neurology
- Psychiatry
- Clinical Practice Improvement
Background:
- Depression is a prevalent yet underrecognized comorbidity in Parkinson's disease (PD).
- Systematic screening is recommended for depression in PD care but is not widely adopted.
- Current clinical practice often lacks formal depression assessment tools for PD patients.
Purpose of the Study:
- To assess the feasibility and impact of implementing a formal depression screening tool in movement disorder clinics for Parkinson's disease patients.
- To evaluate the increase in formal depression screening rates and identify barriers to implementation.
- To examine the effect of screening on depression scores in PD patients.
Main Methods:
- The 15-item Geriatric Depression Scale (GDS-15) was implemented across 5 movement disorder clinics.
- Site-specific workflows were developed, and qualitative interviews were conducted with clinicians and patients.
- Screening rates, reasons for non-screening, and depression scores were analyzed before and after implementation.
Main Results:
- Formal screening increased nearly five-fold, with 88% of PD patients screened during the study period.
- The Geriatric Depression Scale (GDS-15) was used in 59% of screenings, a substantial rise from baseline.
- 45% of patients completing the GDS-15 screened positive for depression, and subsequent follow-up showed significant improvements in depression scores.
Conclusions:
- Formal depression screening using instruments like the GDS-15 is achievable at higher rates in Parkinson's disease care.
- Barriers such as clinician time and logistical challenges exist but can be managed with site-specific processes.
- Optimizing screening rates requires tailored implementation strategies for individual clinical settings.
More Related Videos
10:28Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease
Published on: July 24, 2019
07:26Characterizing the Relationship Between Eye Movement Parameters and Cognitive Functions in Non-demented Parkinson's Disease Patients with Eye Tracking
Published on: September 26, 2019
Related Concept Videos
Parkinson's Disease: Treatment
Parkinson's Disease is primarily a result of the loss of dopaminergic neurons in the substantia nigra pars compacta. The cornerstone of...
Parkinson's Disease: Overview