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Biological-equivalent-dose-based integrated optimization framework for fast-energy-switching Bragg peak FLASH-RT

Yiling Zeng1,2,3, Heng Li4, Qi Zhang1

  • 1Department of Medical Physics, School of Physics and Technology, Wuhan University, Wuhan, China.

Medical Physics
|July 20, 2024
PubMed
Summary

This study introduces an integrated optimization framework for FLASH radiotherapy, improving normal tissue sparing with single beam per fraction schedules. The developed framework effectively compensates for potential dose increases, enhancing treatment safety.

Keywords:
Bragg peak proton therapyFLASH effectequivalent dose in 2 Gysingle beam per fraction

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