Related Experiment Video
Updated: Aug 9, 2026

The Application of 1% Methylene Blue Dye As a Single Technique in Breast Cancer Sentinel Node Biopsy
Published on: June 1, 2019
Who still needs surgical staging of the axilla for invasive breast cancer?
Kathryn Kelley1,2,3, Stephen F Sener2,3
1University of Southern California-Hoag Memorial Hospital Presbyterian Breast Surgical Oncology Fellowship, Los Angeles, California, USA.
Abstract:
Sentinel lymphadenectomy may be safely omitted for postmenopausal patients with low-risk estrogen-receptor-positive cancers who have a negative pretreatment axillary ultrasound. Surgical staging should still be done for patients who are premenopausal or postmenopausal with high-risk estrogen receptor-positive cancers, for those having neoadjuvant chemotherapy, or those with estrogen-receptor-negative or human epidermal growth factor receptor-positive cancers.

