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Evaluation of left ventricular function using digital subtraction angiography.

T Kozuka, M Ohta

    Japanese Circulation Journal
    |July 1, 1985
    PubMed
    Summary
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    Digital subtraction angiography (DSA) effectively assesses left ventricular function and myocardial perfusion in ischemic heart disease patients. This technique shows strong correlation with traditional methods for evaluating ventricular volumes and ejection fraction.

    Area of Science:

    • Cardiology
    • Radiology
    • Medical Imaging

    Background:

    • Ischemic heart disease necessitates accurate assessment of left ventricular function and myocardial perfusion.
    • Traditional methods like cine left ventriculography and 201 Tl myocardial imaging are established but may have limitations.

    Purpose of the Study:

    • To evaluate the efficacy of digital subtraction angiography (DSA) for assessing left ventricular function and myocardial perfusion in patients with ischemic heart disease.
    • To compare DSA-derived parameters with established methods such as cine left ventriculography and 201 Tl myocardial imaging.

    Main Methods:

    • Digital subtraction angiography (DSA) was performed in 45 patients with ischemic heart disease.
    • DSA-derived measurements of end-diastolic volume (EDV), end-systolic volume (ESV), and ejection fraction (EF) were compared with cine left ventriculography.

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  • Regional contractility and inferior wall motion were assessed by DSA and compared with cine left ventriculography.
  • Myocardial perfusion imaging using a modified Radtke's technique via DSA was compared with 201 Tl myocardial imaging in 20 patients.

    • Main Results:

    • DSA showed high correlation with cine left ventriculography for EDV (r=0.92), ESV (r=0.94), and EF (r=0.86).
    • Regional contractility assessment by DSA correlated well with cine left ventriculography (antero-lateral wall: r=0.75; inferior wall: r=0.68).
    • Phase and amplitude analysis of left ventricular function using DSA was successfully applied.
    • DSA-derived myocardial perfusion images demonstrated good coincidence with 201 Tl myocardial images.

    Conclusions:

    • Digital subtraction angiography (DSA) is a valid and applicable technique for objective evaluation of left ventricular function and myocardial perfusion in patients with ischemic heart disease.
    • DSA offers a comprehensive approach, potentially combining functional and perfusion imaging in a single procedure.