Bacillus methanolicus: an emerging chassis for low-carbon biomanufacturing
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Updated: Jun 20, 2025

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Bioprospecting of Extremophilic Microorganisms to Address Environmental Pollution
Published on: December 30, 2021
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Xueting Yang1, Zhaojuan Zheng1, Yu Wang2
1Jiangsu Co-Innovation Center of Efficient Processing and Utilization of Forest Resources, College of Chemical Engineering, Nanjing Forestry University, Nanjing 210037, China.
Trends in Biotechnology
|July 20, 2024
Abstract:
Bacillus methanolicus is a thermophilic methylotrophic bacterium that grows quickly on methanol in sea water-based media. It has been engineered for chemical bioproduction from methanol, but its efficiency needs improvement for industrialization. Synthetic biology approaches such as metabolic modeling and genome editing can reprogram B. methanolicus for low-carbon biomanufacturing.

