Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Decreased Body Temperature01:29

Decreased Body Temperature

604
A decreased body temperature can occur in patients with hypothermia and frostbite. Heat loss with extended cold exposure overpowers the body's ability to create heat, resulting in hypothermia. Core temperature readings help classify hypothermia. Mild hypothermia is temperatures between 32 °C (89.6 °F) and 35°C (95 °F) and is caused by impaired thermoregulation. Moderate hypothermia is temperatures between 28 C (82.4 °F) and 32 °C (89.6 °F) caused by...
604

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Cellular and subcellular localization of the copper transporter CTR1 in human postmortem hippocampus and striatum.

Scientific reports·2026
Same author

Leveraging clinical decision support to minimize sedation gaps in patients receiving rocuronium for rapid sequence intubation.

American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists·2026
Same author

Sanjay Pandey, MBBS, MD, DNB, DM, FIAN, and Aasef Shaikh, MD, PhD.

Seminars in neurology·2026
Same author

Comparative Pulmonary Artery Pressure Response between Large-Bore Thrombectomy and Catheter-Directed Thrombolysis in Patients with Intermediate-High- and High-Risk Pulmonary Embolism.

Journal of vascular and interventional radiology : JVIR·2026
Same author

A Modified Delphi Consensus-Based Comprehensive Checklist and Angoff Standard for Assessment of Competency in Brain Death/Death by Neurologic Criteria Determination.

Critical care medicine·2026
Same author

Integrating Brain Imaging Volumetrics and Quantitative Pupillometry for Predicting Neurologic Deterioration after Large Hemispheric Stroke.

Neurocritical care·2026

Related Experiment Video

Updated: Jun 20, 2025

Esophageal Heat Transfer for Patient Temperature Control and Targeted Temperature Management
06:43

Esophageal Heat Transfer for Patient Temperature Control and Targeted Temperature Management

Published on: November 21, 2017

24.3K

Temperature Control Parameters Are Important: Earlier Preinduction Is Associated With Improved Outcomes Following

Rachel Beekman1, Noah Kim2, Christine Nguyen1

  • 1Department of Neurology, Yale School of Medicine, New Haven, CT.

Annals of Emergency Medicine
|July 21, 2024
PubMed
Summary

Rapid temperature control initiation after cardiac arrest improves patient outcomes. Starting temperature management within 3 hours of hospital arrival is linked to better neurological recovery and survival rates in out-of-hospital cardiac arrest (OHCA) patients.

More Related Videos

In vitro Assessment of Myocardial Protection following Hypothermia-Preconditioning in a Human Cardiac Myocytes Model
08:22

In vitro Assessment of Myocardial Protection following Hypothermia-Preconditioning in a Human Cardiac Myocytes Model

Published on: October 27, 2020

3.0K
Technical Refinement of a Bilateral Renal Ischemia-Reperfusion Mouse Model for Acute Kidney Injury Research
03:13

Technical Refinement of a Bilateral Renal Ischemia-Reperfusion Mouse Model for Acute Kidney Injury Research

Published on: November 3, 2023

2.2K

Related Experiment Videos

Last Updated: Jun 20, 2025

Esophageal Heat Transfer for Patient Temperature Control and Targeted Temperature Management
06:43

Esophageal Heat Transfer for Patient Temperature Control and Targeted Temperature Management

Published on: November 21, 2017

24.3K
In vitro Assessment of Myocardial Protection following Hypothermia-Preconditioning in a Human Cardiac Myocytes Model
08:22

In vitro Assessment of Myocardial Protection following Hypothermia-Preconditioning in a Human Cardiac Myocytes Model

Published on: October 27, 2020

3.0K
Technical Refinement of a Bilateral Renal Ischemia-Reperfusion Mouse Model for Acute Kidney Injury Research
03:13

Technical Refinement of a Bilateral Renal Ischemia-Reperfusion Mouse Model for Acute Kidney Injury Research

Published on: November 3, 2023

2.2K

Area of Science:

  • Emergency Medicine
  • Critical Care Medicine
  • Neuroscience

Background:

  • Temperature control trials in cardiac arrest patients have yielded inconsistent neuroprotective benefits due to variable treatment parameters.
  • The impact of pre-initiation time on temperature control effectiveness remains unclear.

Purpose of the Study:

  • To assess the association between pre-induction time and clinical outcomes in out-of-hospital cardiac arrest (OHCA) patients.
  • To determine if earlier initiation of temperature control improves neurological function and survival.

Main Methods:

  • Retrospective study of 347 OHCA patients treated with temperature control between 2014-2022.
  • Defined pre-induction time as door to temperature control initiation; early initiation was <3 hours.
  • Logistic regression and inverse probability treatment weighting were used to analyze outcomes (neurologic function, survival).

Main Results:

  • Early initiation (<3 hours) was observed in 21.6% of patients (median time 2.5 hours).
  • Late initiation (>3 hours) was seen in 78.4% of patients (median time 5.18 hours).
  • Early temperature control initiation was significantly associated with improved neurologic outcome and survival, even after adjusting for confounding factors.

Conclusions:

  • Shorter pre-induction time for temperature control in OHCA patients correlates with better neurologic outcomes and survival.
  • Early initiation of temperature control in the emergency department may confer significant clinical benefits.
  • Further prospective trials are needed to validate these hypothesis-generating findings.