Related Experiment Video
Updated: Jun 20, 2025

Author Spotlight: A Cost-Effective Genomic Workflow for Advancing Rabies Control in Resource-Limited Settings
Published on: August 18, 2023
Emergence of monkeypox virus in central Argentina: Epidemiological features and first complete genome sequences in
Gonzalo M Castro1, Paola E Sicilia1, Ana Willington2
1Departamento Laboratorio Central, Ministerio de Salud de la Provincia de Córdoba, Tránsito Cáceres de Allende 421, CP 5000, Córdoba, Argentina.
Abstract:
Monkeypox (Mpox) is a zoonotic disease caused by the monkeypox virus (MPXV). MPXV can be transmitted by close contact with lesions, body fluids, respiratory droplets, and contaminated materials. A new pattern of spread among sexual networks has been recently described. The present work aimed to report the epidemiological and genomic characterization of the 2022 MPXV outbreak in central Argentina. A total of 113 scabs and/or lesion swab specimens were studied. MPXV infection was confirmed in 46.0% of the studied patients, all of whom were men. Varicella-zoster virus infection was the most frequent differential diagnosis. Eight complete viral genomes were obtained by next-generation sequencing. The Argentinian sequences were grouped intermingled with other sequences from the 2022 MPXV outbreak, related to samples from the USA, Europe, and Peru. Taken together, our study provided an initial assessment of the genetic and epidemiological characteristics of the 2022 MPXV outbreak in Córdoba, Argentina.
Related Concept Videos
Viral Mutations
Retroviruses
Retrovirus Life Cycles
Viral Recombination
Single Nucleotide Polymorphisms-SNPs

