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Phytochemical profiling and anticancer potential of Memecylon lushingtonii Gamble methanolic crude extracts
C Umamaheswari1,2, Asha S1
1Department of Biotechnology, VFSTR (Deemed to be University), Vadlamudi, Andhra Pradesh, India.
Abstract:
The present investigation examines the anticancer characteristics of phytochemicals derived from Memecylon lushingtonii Gamble (MLG) leaves, concentrating on their efficiency against breast cancer cell lines. Utilising column chromatography, we recovered four different fractions from the methanol extract of MLG leaves. The fourth fraction, rich in bioactive chemicals, displayed substantial cytotoxicity in MTT experiments against MCF-7 cells, indicating powerful anticancer potential. Further investigations revealed a varied array of phytochemicals, including phenols and flavonoids, recognised for their medicinal properties. This discovery emphasises the promise of MLG leaf extracts as a source of anticancer drugs and establishes the framework for further investigations into their mechanisms of action.
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