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Updated: Jun 20, 2025

Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus
Published on: May 16, 2025
Annular papulovesicular lesions with a purpuric center in a female inpatient
David Alvarez Martinez1, Gürkan Kaya1,2, Sébastien Menzinger1,2
1Division of Dermatology and Venereology University Hospital of Geneva Genève Switzerland.
Abstract:
Epidermal multinucleated keratinocytes, or epidermal grape cells, in the absence of any viral infection, are an important histological finding and a clue for the diagnosis of dermatoses induced by external irritation or aggression, dermatitis artefacta, and facticial dermatitis. Thermal damage such as cryogenic injury is part of the spectrum of causes to be evoked in case of their presence.
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