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Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

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Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
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Pulmonary Tuberculosis IV01:26

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Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
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Pulmonary Tuberculosis V01:28

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Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
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Pulmonary Tuberculosis II01:28

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Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
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Pulmonary Tuberculosis I01:29

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Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
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Multifocal Skeletal Tuberculosis - A Case Report.

Ranjith Unnikrishnan1, Ankith Chacko1, Muhammad Jasim1

  • 1Department of Orthopaedics and Spine Surgery, KIMS Health, Trivandrum, India.

Journal of Orthopaedic Case Reports
|July 22, 2024
PubMed
Summary
This summary is machine-generated.

This case report details a rare instance of multifocal skeletal tuberculosis affecting the spine, acetabulum, and sacroiliac joint in an immunocompetent young woman. Early diagnosis and multidisciplinary treatment are crucial for managing this complex condition.

Keywords:
Multifocal skeletal tuberculosisantitubercular treatmentsurgical intervention

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Area of Science:

  • Orthopedics
  • Infectious Diseases
  • Radiology

Background:

  • Tuberculosis (TB) commonly affects the lungs but can manifest in extrapulmonary sites, including bones.
  • Skeletal TB accounts for approximately 10% of extrapulmonary TB cases, with spinal TB being more frequent than sacroiliac (SI) joint TB.
  • Multifocal skeletal TB, especially in immunocompetent individuals, presents diagnostic challenges.

Observation:

  • A 19-year-old immunocompetent female presented with severe pain, weight loss, and limited mobility.
  • Initial treatment with alternative medicine led to delays in diagnosis and disease progression.
  • Radiological imaging revealed extensive destruction of the spine, acetabulum, and SI joint with associated abscess formation.

Findings:

  • The case highlights concurrent involvement of the spine, acetabulum, and SI joint by tuberculosis.
  • Histopathological and microbiological examinations confirmed the diagnosis of multifocal skeletal TB.
  • Combined surgical intervention (debridement and stabilization) and antitubercular therapy resulted in significant clinical improvement.

Implications:

  • This case underscores the importance of considering TB in the differential diagnosis of destructive skeletal lesions, even in immunocompetent patients.
  • Delayed diagnosis and treatment, particularly due to reliance on alternative medicine, can lead to severe morbidity.
  • A multidisciplinary approach is essential for effective management of complex multifocal skeletal TB cases.