The role of C-reactive protein/albumin ratio and prognostic nutritional index in the diagnosis of complicated acute appendicitis
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View abstract on PubMed
Summary
This summary is machine-generated.The CRP/albumin ratio (CAR) was higher in complicated appendicitis cases, but neither CAR nor PNI independently predicted complicated appendicitis. Further research is needed to explore their predictive value.
Area Of Science
- Medical research
- Inflammation markers
- Surgical outcomes
Background
- C-reactive protein (CRP) and albumin levels are altered during inflammation.
- The CRP/albumin ratio (CAR) and prognostic nutritional index (PNI) are potential prognostic indicators.
- Differentiating complicated from non-complicated acute appendicitis (AA) is clinically important.
Purpose Of The Study
- To evaluate the clinical significance of CAR and PNI in distinguishing complicated AA.
- To identify independent predictors for complicated appendicitis.
Main Methods
- Retrospective analysis of 187 patients with AA.
- Comparison of demographic, clinical, laboratory, and pathological data between non-complicated and complicated AA groups.
- Logistic regression analysis to identify predictors of complicated AA.
Main Results
- The complicated AA group was older and had a significantly higher CAR.
- Patients with complicated AA had a longer hospital stay.
- Neither CAR nor PNI were found to be independent predictors of complicated AA in multivariate analysis.
Conclusions
- CAR and PNI are not independent predictors for complicated acute appendicitis.
- Age was a significant factor in univariate analysis but not in multivariate analysis.
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