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[Primary laryngeal lymphoma: a case report].
Madiha Chalout1, Anouar Bouhlala1, Oumaima El Masfioui1
1Université Sidi Mohamed Ben Abdellah, Faculté de Médecine et de Pharmacie de Fès, Centre Hospitalier Universitaire HASSAN II, Fès, Service Oto-Rhino-Laryngologie et Chirurgie Cervico-Faciale, Fès, Maroc.
The Pan African Medical Journal
|July 22, 2024
Summary
Primary laryngeal lymphoma, a rare cancer, can present with varied symptoms like dysphagia. This case highlights successful chemotherapy and radiotherapy for diffuse large B-cell lymphoma, emphasizing tailored treatment for this uncommon condition.
Area of Science:
- Oncology
- Hematology
Background:
- Primary laryngeal lymphoma is an exceedingly rare malignancy, constituting less than 1% of all laryngeal cancers.
- Optimal management strategies for laryngeal lymphoma remain controversial due to its rarity and diverse clinical presentations.
Observation:
- A 64-year-old non-smoking woman presented with dysphagia and a foreign body sensation.
- Laryngoscopy and biopsies identified a polyploid tumor on the left epiglottic fold.
Findings:
- The tumor was diagnosed as diffuse large B-cell lymphoma.
- The patient received chemotherapy followed by radiotherapy, achieving significant improvement and no local recurrence at a 2-year follow-up.
Implications:
- This case underscores the importance of a specific diagnostic and therapeutic approach for primary laryngeal lymphoma.
- Successful multimodal treatment suggests a viable management pathway for this rare laryngeal cancer.
