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Complex Regional Pain Syndrome in a Non-traumatic Case: A Case Report
Yacoub Abuzied1, Mohammad Jaber2, Mona Hafiz3
1Department of Nursing, Rehabilitation Hospital, King Fahad Medical City, Riyadh, SAU.
Cureus
|July 22, 2024
Summary
This case report details a rare instance of non-traumatic Complex Regional Pain Syndrome (CRPS), highlighting diagnostic challenges. Further research is needed for better understanding and diagnosis of this neuropathic pain condition.
Area of Science:
- Neurology
- Pain Medicine
- Case Reports
Background:
- Complex Regional Pain Syndrome (CRPS) is a neuropathic pain disorder often associated with trauma, surgery, stroke, or spinal cord injury.
- It manifests with severe pain, edema, motor deficits, and autonomic dysfunction, significantly impacting quality of life.
Observation:
- This report presents a unique case of non-traumatic CRPS in a 39-year-old male with a seven-year history of severe right shoulder-hand pain.
- The patient experienced burning pain and weakness without any preceding trauma or fracture, indicating an atypical presentation.
Findings:
- Standard treatments, including surgical and pharmaceutical interventions, proved ineffective in alleviating the patient's symptoms.
- The diagnosis of CRPS was challenging due to the absence of a clear precipitating event and the lack of specific diagnostic imaging or laboratory tests.
Implications:
- This case underscores the need for expanded diagnostic criteria and novel diagnostic tools for non-traumatic CRPS.
- Further research is crucial for a comprehensive understanding of the pathophysiology and development of effective therapeutic strategies for this complex pain syndrome.

