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Chemical-Induced Skin Carcinogenesis Model Using Dimethylbenz[a]Anthracene and 12-O-Tetradecanoyl Phorbol-13-Acetate DMBA-TPA
Published on: December 19, 2019
A Case Report of Juvenile-Onset Recurrent Respiratory Papillomatosis
Farhana Kamaruzaman1,2, Rohaida Ibrahim1, Nik Khairani Nik Mohd1
1Department of Otorhinolaryngology, Hospital Sultanah Nur Zahirah, Kuala Terengganu, MYS.
Insights
Pediatric laryngeal papillomatosis, a rare chronic condition, was diagnosed in a four-year-old girl. Surgical excision of the laryngeal papilloma was performed to restore airway and voice.
Area of Science:
- Otolaryngology
- Pediatric Surgery
- Laryngeal Pathology
Background:
- Laryngeal papilloma is the most common benign laryngeal neoplasm in children.
- Laryngeal papillomatosis is a rare, chronic condition affecting the larynx in pediatric patients.
- Vertical transmission during labor is a potential route of acquisition.
Abstract:
The most common benign laryngeal neoplasm in children is a papilloma. Laryngeal papillomatosis is a chronic disease and is rare in children. We report the case of a four-year-old Malay girl in whom chronic laryngeal papillomatosis, most likely acquired vertically during labor, was detected. She presented with hoarseness of voice for three years, and a flexible laryngoscopy examination revealed features of papilloma in the glottis area. The patient underwent direct laryngoscopy followed by excision of mass using the cold instrument. Surgical intervention is the primary treatment modality for laryngeal papillomatosis to maintain airway patency and voice quality.
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