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Minimizing risk while maximizing opportunity: The infectious disease organ offer process survey
Katya Prakash1, Kapil K Saharia1, Andrew Karaba2
1Institute of Human Virology, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Summary
Transplant infectious disease (TID) physicians generally agree on organ acceptability but vary on post-transplant management. The study highlights the need for more data to optimize donor acceptance and recipient care in transplantation.
Area of Science:
- Transplant Infectious Diseases
- Organ Transplantation
- Infectious Disease Management
Background:
- Assessing organ donors with infections is critical in transplantation.
- Understanding physician practices for donor evaluation and post-transplant care is essential.
Purpose of the Study:
- To understand how transplant infectious disease (TID) physicians assess donors with infections.
- To describe post-transplant management strategies for recipients.
Main Methods:
- A survey with 10 organ offer scenarios was developed.
- Responses from TID clinicians were collected and analyzed using descriptive statistics.
Main Results:
- 113 physicians responded; 85 completed all cases.
- General agreement on organ acceptability, with some divergence for specific infections (e.g., influenza, TB, MDR Acinetobacter).
- Significant variation observed in post-transplant management strategies.
Conclusions:
- Donor offer evaluation by TID clinicians is complex.
- Identified areas for improvement include risk mitigation, recipient factors, and evidence-based management data.
- Further data generation can enhance organ utilization and recipient outcomes.
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