Related Experiment Video
Updated: Jun 20, 2025

A Reliable and Reproducible Critical-Sized Segmental Femoral Defect Model in Rats Stabilized with a Custom External Fixator
Published on: March 24, 2019
Ribbing disease of the femur: a rare entity
Ahmad Alnaggar1, Ali Hassan2, Maryam Alkhaja1
1Radiology Department, Salmaniya Medical Complex, Manama, Bahrain.
Ribbing disease, a rare bone dysplasia, typically affects adults but this case details a unique presentation in a 20-year-old male with isolated femur involvement. This highlights diagnostic challenges and the need to consider this condition in chronic limb pain evaluations.
Area of Science:
- Orthopedics
- Radiology
- Skeletal Dysplasias
Background:
- Ribbing disease is a rare, benign bone dysplasia.
- Characterized by progressive cortical thickening of long bone diaphyses in adults.
- Limited literature exists on its radiological progression and anatomical distribution, with single-bone involvement being uncommon.
Purpose of the Study:
- To report a unique case of Ribbing disease.
- To describe its presentation localized to the femur in a young adult.
- To discuss diagnostic challenges and implications for patient management.
Main Methods:
- Case report of a 20-year-old male with chronic thigh pain.
- Radiographic imaging (initial and follow-up).
- Magnetic Resonance Imaging (MRI) and Computed Tomography (CT) for detailed bone assessment.
Main Results:
- Initial radiographs were unremarkable; follow-up revealed focal fusiform widening and cortical thickening of the left femur.
- MRI showed circumferential cortical thickening with bone marrow edema.
- CT confirmed significant cortical thickening and near-obliteration of the intramedullary cavity.
Conclusions:
- This case presents an atypical, femur-exclusive manifestation of Ribbing disease in a young patient.
- Diagnostic challenges were encountered, including misinterpretation leading to unnecessary radiofrequency ablation.
- Emphasizes the importance of considering Ribbing disease in the differential diagnosis of chronic limb pain, especially with unusual radiological findings.
Related Concept Videos
Bones of the Lower Limb: Femur and Patella
Bones of the Lower Limb: Tibia and Fibula
Bones of the Upper Limb: Radius
The radius has a nail-shaped head, and a...
Bone Disorders
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Bones of the Upper Limb: Humerus
Disorders of the Skeletal Muscle
Musculoskeletal disorders
Musculoskeletal disorders involve injuries and conditions affecting the skeletal muscles and associated connective tissues. These disorders can arise from acute biomechanical stresses or chronic overuse and can occur across different age groups. Common injuries include sprains, fractures, and muscular strains, often resulting from...

