Related Experiment Video
Updated: Aug 5, 2026
07:35
Methods for Studying the Mechanisms of Action of Antipsychotic Drugs in Caenorhabditis elegans
Published on: February 4, 2014
[EEG changes during clozapin administration compared to other neuroleptic agents. Controlled case study in a
International Pharmacopsychiatry
|January 1, 1979
Abstract:
A hyperactive mentally retarded patient receiving clozapin and other major tranquilizers had an unexpected seizure. The EEG revealed severe pathological patterns which disappeared after discontinuation of clozapin and could be reproduced as a function of clozapin medication. Other major tranquilizers had no particular effects. This study demonstrates how we determined whether clozapin or other major tranquilizers had seizure-promoting effects in a particular patient.
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