Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Positron Emission Tomography01:29

Positron Emission Tomography

4.1K
Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body...
4.1K
Imaging Studies II: Positron Emission Tomography and Scintigraphy01:25

Imaging Studies II: Positron Emission Tomography and Scintigraphy

100
Positron Emission Tomography (PET) is a medical imaging technique that provides crucial insights into the body's physiological functions at a molecular level. It is an indispensable resource for diagnosing, staging, and monitoring various illnesses, notably cancer, neurological disorders, and cardiovascular conditions.
Fundamental Principles of PET
100
Radiological Investigation III: Pulmonary Angiogram and PET Scan01:13

Radiological Investigation III: Pulmonary Angiogram and PET Scan

89
Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
89
Computed Tomography01:10

Computed Tomography

4.4K
Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
4.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A server-based solution for misregistration correction in PET/CT using limited-coverage and data-driven gated CT.

Medical physics·2026
Same author

LDM-Morph: Latent diffusion model guided deformable image registration.

Pattern recognition·2026
Same author

The Impact of Radiation Dose to Bowel on the Risk of Developing Gastrointestinal Toxicities When Treating Abdominopelvic Soft-Tissue Sarcomas With Preoperative Radiation Therapy.

Advances in radiation oncology·2026
Same author

Bayesian Learning to Reduce Cardiac Risk of Patients With Locally Advanced Non-Small Cell Lung Cancer Based on Personalized Radiation Therapy Prescription.

International journal of radiation oncology, biology, physics·2025
Same author

Improving data-driven gated (DDG) PET and CT registration in thoracic lesions: a comparison of AI registration and DDG CT.

EJNMMI physics·2025
Same author

Automatic trending and analysis of SPECT quality assurance with artificial intelligence optical character recognition.

Medical physics·2025

Related Experiment Video

Updated: Jun 20, 2025

Positron Emission Tomography-based Dose Painting Radiation Therapy in a Glioblastoma Rat Model using the Small Animal Radiation Research Platform
07:57

Positron Emission Tomography-based Dose Painting Radiation Therapy in a Glioblastoma Rat Model using the Small Animal Radiation Research Platform

Published on: March 24, 2022

2.8K

Data-driven gated positron emission tomography/computed tomography for radiotherapy.

Tinsu Pan1, Dershan Luo2

  • 1Department of Imaging Physics, M.D. Anderson Cancer Center, University of Texas, United States.

Physics and Imaging in Radiation Oncology
|July 23, 2024
PubMed
Summary

Software-based data-driven gated (DDG) PET/CT offers improved accuracy for radiotherapy planning and treatment response assessment compared to older hardware-gated methods. This advanced imaging technique corrects motion artifacts and provides quantitative data for precise tumor targeting.

Keywords:
Data-driven gated CTData-driven gated PETData-driven gated PET/CTMisregistration correctionPET/CTRespiratory gatingRespiratory motionTumor motion

More Related Videos

PET and MRI Guided Irradiation of a Glioblastoma Rat Model Using a Micro-irradiator
10:48

PET and MRI Guided Irradiation of a Glioblastoma Rat Model Using a Micro-irradiator

Published on: December 28, 2017

9.5K
Radiosynthesis, Quality Control, and Small Animal Positron Emission Tomography Imaging of 68Ga-Labelled Nano Molecules
09:55

Radiosynthesis, Quality Control, and Small Animal Positron Emission Tomography Imaging of 68Ga-Labelled Nano Molecules

Published on: October 4, 2024

343

Related Experiment Videos

Last Updated: Jun 20, 2025

Positron Emission Tomography-based Dose Painting Radiation Therapy in a Glioblastoma Rat Model using the Small Animal Radiation Research Platform
07:57

Positron Emission Tomography-based Dose Painting Radiation Therapy in a Glioblastoma Rat Model using the Small Animal Radiation Research Platform

Published on: March 24, 2022

2.8K
PET and MRI Guided Irradiation of a Glioblastoma Rat Model Using a Micro-irradiator
10:48

PET and MRI Guided Irradiation of a Glioblastoma Rat Model Using a Micro-irradiator

Published on: December 28, 2017

9.5K
Radiosynthesis, Quality Control, and Small Animal Positron Emission Tomography Imaging of 68Ga-Labelled Nano Molecules
09:55

Radiosynthesis, Quality Control, and Small Animal Positron Emission Tomography Imaging of 68Ga-Labelled Nano Molecules

Published on: October 4, 2024

343

Area of Science:

  • Medical Imaging
  • Radiotherapy Physics
  • Nuclear Medicine

Background:

  • Hardware-based 4D PET/CT has been the standard for motion-compensated imaging in radiotherapy.
  • Advancements in PET instrumentation and software have led to new imaging techniques.

Purpose of the Study:

  • To review data-driven gated (DDG) PET/CT as a replacement for hardware-based 4D PET/CT.
  • To highlight the benefits of DDG PET/CT for radiotherapy, including improved treatment response assessment, tumor motion evaluation, and target delineation.
  • To discuss the integration of DDG PET/CT into whole-body (WB) PET/CT protocols.

Main Methods:

  • Systematic literature review of 4D PET/CT, PET instrumentation, DDG PET, DDG CT, and DDG PET/CT.
  • Discussion of large axial field-of-view (AFOV) PET detectors.
  • Review of clinical results for DDG PET and DDG PET/CT.

Main Results:

  • DDG PET demonstrated comparable or superior performance to hardware-gated 4D PET.
  • DDG CT is more compatible with DDG PET than 4D CT, enabling its use in radiotherapy.
  • DDG PET/CT can be integrated into WB PET/CT scans with a scan time under 15 minutes using scanners with at least a 25 cm AFOV PET detector.

Conclusions:

  • DDG PET/CT effectively corrects misregistration and tumor motion artifacts in WB PET/CT.
  • It provides quantitative PET and tumor motion information essential for registered PET/CT in radiotherapy.
  • DDG PET/CT enhances the accuracy and efficiency of radiotherapy planning and delivery.