[The histological study: an important parameter in checking the use of anabolics. Past, present, future?]

The histological methods used in checking the administration of oestrogens to fattening calves, introduced in the Netherlands in 1967, are discussed. Because of the increased use of combined treatment with oestrogens and androgens (both synthetic and natural), the suitability of the above histological techniques has become doubtful. Moreover, exogenous natural steroid hormones were not found to constitute any hazard to public health and could be safely used in husbandry. If administration of such anabolics is permitted the reasons for histological examination would cease to exist.