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[Genital mycoplasma infections].

R Werni, P A Mårdh

    Zeitschrift Fur Hautkrankheiten
    |September 15, 1985
    PubMed
    Summary

    Mycoplasma hominis and Ureaplasma urealyticum are common in young adults. These bacteria may cause various infections, including urethritis, endometritis, and neonatal meningitis, with specific antibiotic treatments recommended.

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    Area of Science:

    • Microbiology
    • Infectious Diseases
    • Gynecology

    Context:

    • Mycoplasma hominis and Ureaplasma urealyticum are frequently detected in young, sexually active individuals.
    • Previous research on their clinical significance has yielded conflicting findings.
    • These microorganisms are often found in the urogenital tract.

    Purpose:

    • To investigate the clinical significance and etiological role of Mycoplasma hominis and Ureaplasma urealyticum.
    • To clarify the association between these mycoplasmas and specific human infections.
    • To review diagnostic approaches and treatment strategies for mycoplasma infections.

    Summary:

    • Ureaplasma urealyticum is a potential cause of non-gonococcal urethritis.
    • Mycoplasma hominis is implicated in postpartum endometritis, salpingitis, parametritis, and sepsis.
    • Mycoplasma hominis can also cause neonatal meningitis and encephalitis.
    • Diagnosis relies on organism isolation, exclusion of other pathogens, and serological antibody titer changes.
    • Tetracycline is the primary treatment; clindamycin is an alternative for M. hominis, and erythromycin for U. urealyticum.

    Impact:

    • Provides a clearer understanding of the pathogenic potential of Mycoplasma hominis and Ureaplasma urealyticum.
    • Highlights the importance of considering these organisms in the differential diagnosis of genitourinary and neonatal infections.
    • Informs clinical management by outlining diagnostic criteria and effective therapeutic options.

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