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The nutritional state and nutrition

J A Dodge

    Acta Paediatrica Scandinavica. Supplement
    |January 1, 1985
    PubMed

    Insights

    Children with cystic fibrosis often experience poor growth and development due to increased nutritional needs and low food intake. Nutritional interventions, including increased dietary fat and supplements, show promise for improving their health outcomes.

    Area of Science:

    • Pediatric Nutrition
    • Cystic Fibrosis Research
    • Growth and Development

    Background:

    • Children with cystic fibrosis (CF) typically exhibit low birth weight, reduced height and weight during childhood, and delayed bone age and puberty compared to the general population.
    • Underweight in CF is more closely linked to respiratory issues than malabsorption.
    • Nutritional requirements in CF may be increased (up to 150% of recommended daily allowance), yet food intake is often insufficient, hindering growth.

    Purpose of the Study:

    • To review current understanding of nutritional challenges in children with cystic fibrosis.
    • To explore emerging nutritional strategies for improving growth and overall health in pediatric CF patients.
    • To evaluate the efficacy and place of various nutritional interventions.

    Main Methods:

    • Literature review of studies on cystic fibrosis nutrition.
    • Analysis of the correlation between respiratory condition, malabsorption, and underweight.
    • Examination of the impact of dietary fat, pancreatic enzyme supplements, elemental diets, and intravenous nutrition.

    Main Results:

    • Increased dietary fat, enabled by modern pancreatic supplements, is a key nutritional strategy.
    • Supplementary nutrition via elemental diets or intravenous hyperalimentation has shown promising results in some studies.
    • Oral essential fatty acid supplements are under evaluation, while intravenous fat emulsions are not currently recommended.

    Conclusions:

    • Optimizing nutrition is crucial for improving the health and infection resistance of children with cystic fibrosis.
    • Modern pancreatic enzyme replacement therapy facilitates increased dietary fat intake.
    • Further research is needed to fully establish the role of oral essential fatty acid supplements.

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