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Updated: Jun 19, 2025

Free Radicals in Chemical Biology: from Chemical Behavior to Biomarker Development
Published on: April 15, 2013
Recent Progress in Free Radical Transformations of Allenamides
Yongchun Liu1, Zimin Wang1, Rui Li1
1College of Energy Chemicals and Environment, Sichuan Vocational and Technical College, Suining 629200, People's Republic of China.
Abstract:
Allenamides are special allenes, and the unique reactivity, selectivity (both stereoselective and regionally selective) and stability of allenamides have been widely studied. In this review, the development of the free radical transformation of allenamides over the last few years will be summarized. This review discusses in detail in three parts: intermolecular radical addition to C- X (X = N, S, O, Se) bonds, metal salt mediated cyclization of allenamides, and photocatalytic cyclization of allenamides. In addition, reasonable details of the mechanisms are provided for the vast majority of these transformations.
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