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Updated: Jun 19, 2025

Intramucosal Inoculation of Squamous Cell Carcinoma Cells in Mice for Tumor Immune Profiling and Treatment Response Assessment
Published on: April 22, 2019
Concurrent squamous cell carcinoma and non-hodgkin lymphoma: a rare case report and multidisciplinary approach
Abdulwahid Salih1,2, Ari Abdullh1,3, Hiwa Baba1,4
1Smart Health Tower, Sulaymaniyah, Iraq.
Introduction:
Squamous cell carcinoma (SCC) is a skin malignancy typically treated with surgical resection. Non-Hodgkin lymphoma (NHL) is a group of lymphoid tissue malignancies treated with various strategies, including chemotherapy and radiotherapy.
Case Presentation:
A 64-year-old male with prior SCC presented with a new scalp lesion. Examination revealed an elevated, irregular, non-tender lesion with mild yellow discoloration. Imaging showed a scalp lesion, cervical lymphadenopathies, and a well-defined mass. Ultrasonography uncovered lymph node involvement and splenomegaly. Fine needle aspiration, biopsy, and immune stains of the lymph node confirmed NHL. Wide local excision of the scalp lesion, reconstruction, and lymph node biopsies were performed, confirming SCC and NHL. The patient received radiotherapy and chemotherapy.
Conclusion:
This unique rare case emphasizes the complex interplay of SCC and NHL, necessitating vigilant SCC patient follow-up.

