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Published on: October 18, 2019
Methoxide-Enabled Zirconium-Catalyzed Migratory Alkene Hydrosilylation
Orsola A Luongo1, Miran Lemmerer1, Sanne L Albers1
1Department of Chemistry-BMC, Uppsala University, Husargatan 3, 75237, Uppsala, Sweden.
Abstract:
A zirconocene dichloride-catalyzed alkene hydrosilylation is reported that can be applied to non-activated and conjugated terminal and internal alkenes. It involves a catalytic Zr-walk process and leads to a selective conversion to the linear product. Lithium methoxide serves as mild catalyst activating agent, which significantly increases the applicability and operational simplicity in comparison to earlier zirconium(II)-based protocols. Supported by additional experiments and calculations, a mechanism via zirconium(IV) intermediates is proposed. Due to the benign nature and ready-availability of the zirconium catalyst, the reaction is an attractive alternative to established alkene hydrosilylation methods.
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