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Published on: March 30, 2018
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Cardiac Malignant Lymphoma with Diffuse Extension to the Left Ventricle
Daichi Terunuma1, Masanobu Miura1, Ko Teshima2
1Department of Cardiology, Iwate Prefectural Central Hospital, Japan.
Internal Medicine (Tokyo, Japan)
|July 24, 2024
Summary
Malignant cardiac lymphoma, a rare condition, can diffusely affect the left ventricle. Chemotherapy improved cardiac function in a patient with this heart lymphoma, demonstrating treatment efficacy.
Area of Science:
- Cardiology
- Oncology
- Pathology
Background:
- Malignant cardiac lymphoma is an uncommon diagnosis.
- Typically presents as right-sided cardiac nodules.
- This case highlights atypical diffuse left ventricular involvement.
Purpose of the Study:
- To report a rare case of malignant cardiac lymphoma with diffuse left ventricular extension.
- To describe the diagnostic findings and treatment of this condition.
- To illustrate the potential for cardiac function improvement with chemotherapy.
Main Methods:
- Patient presentation: Dyspnea and malaise in a woman in her 60s.
- Diagnostic imaging: Echocardiography revealed left ventricular hypertrophy (LVH); MRI showed diffuse delayed contrast enhancement.
- Invasive procedures: Cardiac catheterization and myocardial biopsy confirmed heart failure due to cardiac malignant lymphoma.
Main Results:
- Diagnosis of malignant cardiac lymphoma with diffuse left ventricular infiltration.
- Mild diastolic dysfunction observed despite significant left ventricular hypertrophy.
- Successful treatment with chemotherapy led to improved and maintained cardiac function.
Conclusions:
- Malignant cardiac lymphoma can present with diffuse left ventricular involvement, deviating from typical presentations.
- Multimodality imaging and biopsy are crucial for diagnosis.
- Chemotherapy can effectively manage cardiac lymphoma, leading to functional recovery.
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