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Updated: Jun 19, 2025

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A Model of Self-limited Acute Lung Injury by Unilateral Intra-bronchial Acid Instillation
Published on: August 30, 2019
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COVID-19-Induced Acute Laryngitis: A Case Series
Georgia K Tsiouma1, Anastasia A Oikonomou1, Stavros N Nikitopoulos1
1ENT Department of General Hospital of Volos "Achillopouleio", Volos, Thessaly, Greece.
Summary
This study identifies a new COVID-19 symptom: acute laryngitis with specific throat inflammation and white lesions. Early diagnosis via laryngoscopy and prompt treatment ensure a good prognosis for COVID-19 patients.
Area of Science:
- Otolaryngology
- Infectious Diseases
- Virology
Background:
- COVID-19 (Coronavirus Disease 2019) presents with diverse clinical manifestations.
- Acute laryngitis is a recognized complication, but specific endoscopic findings require further elucidation.
Purpose of the Study:
- To describe a novel clinical presentation of COVID-19 characterized by acute laryngitis.
- To detail the characteristic endoscopic laryngeal findings associated with this condition.
- To analyze the treatment and prognosis of affected patients.
Main Methods:
- A single-center descriptive case series analysis.
- Inclusion of 23 patients diagnosed with COVID-19 and acute laryngitis.
- Recording of demographic, clinical, endoscopic, laboratory, and treatment data.
Main Results:
- Patients presented with acute odynophagia and an erythematous larynx with white, undetachable supraglottic lesions.
- Pooling of saliva in pyriform fossae predicted hospitalization (P < 0.001).
- All patients responded to corticosteroids and antibiotics, with no need for intubation or tracheostomy.
Conclusions:
- COVID-19-induced laryngitis should be suspected in patients with COVID-19 and acute odynophagia.
- Fiberoptic laryngoscopy is crucial for diagnosis.
- Timely treatment leads to favorable outcomes and minimizes airway complications.
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