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Updated: Jun 22, 2026

Assessment of Age-related Changes in Cognitive Functions Using EmoCogMeter, a Novel Tablet-computer Based Approach
Published on: February 14, 2014
A perspective on brain-age estimation and its clinical promise
Christian Gaser1,2,3, Polona Kalc4, James H Cole5,6
1Structural Brain Mapping Group, Department of Neurology, Jena University Hospital, Jena, Germany. christian.gaser@uni-jena.de.
Abstract:
Brain-age estimation has gained increased attention in the neuroscientific community owing to its potential use as a biomarker of brain health. The difference between estimated and chronological age based on neuroimaging data enables a unique perspective on brain development and aging, with multiple open questions still remaining in the brain-age research field. This Perspective presents an overview of current advancements in the field and envisions the future evolution of the brain-age framework before its potential deployment in hospital settings.
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