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Related Concept Videos

Cancer Survival Analysis01:21

Cancer Survival Analysis

336
Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
336

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Updated: Jun 19, 2025

A Quantitative Sensory Testing Paradigm to Obtain Measures of Pain Processing in Patients Undergoing Breast Cancer Surgery
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Patient-Reported Outcomes 10 Years After Breast-Conserving Surgery for Early-Stage Breast Cancer.

Laura S Dominici1,2,3, Alison Laws1,2,3,4, Mirelle Lagendijk1,2,5

  • 1Division of Breast Surgery, Department of Surgery, Brigham and Women's Hospital, Boston, MA, USA.

Annals of Surgical Oncology
|July 24, 2024
PubMed
Summary
This summary is machine-generated.

Long-term patient-reported outcomes (PROs) after breast-conserving surgery (BCS) show generally high physical and psychological well-being. These findings highlight the importance of assessing PROs in breast cancer survivorship for value-based care.

Keywords:
Breast cancerBreast-conserving surgeryPatient-reported outcomesQuality of lifeSurvivorship

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Area of Science:

  • Oncology
  • Surgical Oncology
  • Health Outcomes Research

Background:

  • Patient-reported outcomes (PROs) are crucial for value-based healthcare.
  • Limited data exist on long-term PROs following breast-conserving surgery (BCS).

Purpose of the Study:

  • To assess long-term health-related quality of life (HRQoL) in patients who underwent BCS.
  • To identify factors associated with PRO scores in breast cancer survivors.

Main Methods:

  • A cross-sectional study surveyed 437 patients 10.4 years post-BCS.
  • PROs were measured using BREAST-Q and EORTC QLQ instruments.
  • Multivariable linear regression analyzed factors influencing PRO scores.

Main Results:

  • Physical and psychological well-being scores were generally high.
  • Sexual well-being and satisfaction with breasts showed more variability.
  • Most patients had early-stage disease and received adjuvant radiation therapy.

Conclusions:

  • BCS is associated with sustained quality of life in breast cancer survivors.
  • Long-term PRO assessment is vital for understanding survivorship.
  • These data offer reference values for interpreting PROs in BCS patients within value-based care frameworks.