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Published on: October 15, 2021
Knowledge, Attitude and Practice Toward Intracerebral Hemorrhage Prevention Among Patients Taking Oral Anticoagulants
Wei Xiao1, Yanqiong Liu2, Hua Tang3
1Department of Neurosurgical Care Unit, Changde Hospital, Xiangya School of Medicine, Central South University, Changde, 415003, People's Republic of China.
Insights
Patients on oral anticoagulation (OAC) have poor knowledge and attitudes towards preventing intracerebral hemorrhage (ICH). Their practice is influenced by age, medication, and attitude, not knowledge.
Area of Science:
- Medical research
- Clinical practice
- Patient safety
Background:
- Intracerebral hemorrhage (ICH) affects up to 1% of oral anticoagulation (OAC) users annually.
- Understanding patient knowledge, attitude, and practice (KAP) is crucial for ICH prevention in OAC users.
Purpose of the Study:
- To explore the knowledge, attitude, and practice (KAP) regarding ICH prevention among patients using OACs.
- To analyze the relationships between KAP and demographic/medication factors.
Main Methods:
- A multicenter cross-sectional survey involving 536 OAC patients.
- Self-administered questionnaires assessed KAP towards ICH prevention.
- Structural equation modeling analyzed KAP relationships.
Main Results:
- Average KAP scores indicated insufficient knowledge and negative attitudes, but proactive practice.
- Rivaroxaban users had lower knowledge but higher attitude/practice scores than Warfarin/Dabigatran users.
- Attitude positively impacted practice; knowledge negatively impacted attitude and practice.
Conclusions:
- OAC patients demonstrate inadequate knowledge and attitudes concerning ICH prevention.
- Practice scores are influenced by age, OAC type, and attitude, underscoring the need for targeted interventions.
Background:
Intracerebral hemorrhage (ICH) affects up to 1% of chronic oral anticoagulation (OAC) users per year. This study explored the knowledge, attitude and practice (KAP) towards ICH prevention among patients taking OACs.
Methods:
This multicenter cross-sectional survey was conducted at 4 hospitals from February to May 2023, and a self-administered questionnaire was developed to assess KAP toward ICH prevention among patients taking OACs. Structural equation modeling was used to assess the relationship between KAP.
Results:
A total of 536 valid questionnaires (67.25%) were analyzed, from 43.8% participants on Warfarin, 40.5% on Rivaroxaban and 15.7% on Dabigatran. The average knowledge, attitudes and practice scores were 9.22, 24.11, and 28.01 out of 16, 35 and 40, respectively. Participants who received Rivaroxaban had lower knowledge scores but higher attitude and practice store compared to those who received Warfarin or Dabigatran (all p < 0.001). According to Structure Equation Modeling, attitude had direct positive effect on practice (β = 0.694 [0.603-0.804], p = 0.012), while knowledge had direct negative effect on attitude (β = -2.077 [-2.507-1.651], p = 0.013), as well as negative effect on practice, both direct (β = -0.450[-0.689-2.03], p=0.012), and indirect (β = -1.441 [-1.928-1.192], p = 0.004).
Conclusion:
Patients taking OACs showed insufficient knowledge, negative attitude and proactive practice regarding ICH; practice scores were affected by age, type of anticoagulation medication, and attitude rather than knowledge.
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