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Updated: Jun 19, 2025

Isolation of Neonatal Extrahepatic Cholangiocytes
Published on: June 5, 2014
Neonatal Graves Disease Masquerading as Hemochromatosis
Liesbeth Maggiotto1, Steven D Mittelman2, Roja Fallah3
1Division of Neonatology, Department of Pediatrics, UCLA David Geffen School of Medicine, Los Angeles, CA 90095, USA.
Abstract:
Thyroid autoimmunity is extremely common in the adult population and can affect pregnancy outcomes. Signs in the newborn can range from absent to severe, making the diagnosis easy to miss. We present an interesting case of neonatal Graves disease associated with intrauterine growth restriction, premature delivery, and liver failure with severely high ferritin, thought to be secondary to hemochromatosis. Treatment of the underlying hyperthyroidism caused a rapid resolution of the elevated ferritin and liver failure. This report highlights the importance of considering Graves disease in newborns with liver failure of unknown etiology.
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