A Rare Recurrence of Guillain-Barré Syndrome

Guillain-Barré syndrome (GBS) is an autoimmune polyneuroradiculopathy that is often characterized by progressive motor and sensory deficits. GBS often follows a particular trigger and is more common in males. Recurrent GBS is uncommon, but it can occur in 2-3% of patients with a prior GBS episode. Although recurrent GBS is generally milder than the initial episode, exceptions are possible, as illustrated in the case presented here. For both monophasic or recurrent GBS, treatment usually centers on supportive care, intravenous immunoglobulin administration, and plasmapheresis, with steroids having no impact on the prognosis. We present a case in which an 80-year-old woman with severe recurrent GBS experienced rapid deterioration within hours.