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Updated: Jun 19, 2025

Microfluidics in Assessing Platelet Function
Published on: November 8, 2024
Severe platelet transfusion refractoriness after thoracoabdominal aneurysm repair
Claire M Motyl1, S Danielle Phillips1, Jori E May2
1Division of Vascular Surgery, University of Alabama at Birmingham, Birmingham, AL.
Abstract:
Severe thrombocytopenia after thoracoabdominal aortic aneurysm repair poses a significant clinical risk in the immediate postoperative period. Understanding the mechanisms of refractoriness to platelet transfusion is relevant to supporting thrombocytopenic patients postoperatively. We present the case of a 76-year-old woman with refractory thrombocytopenia secondary to alloimmunization following open repair of a Crawford extent IV thoracoabdominal aneurysm. The patient provided written informed consent for the report of her case details and imaging studies.
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