Pembrolizumab-induced vasculitis demonstrated by FDG-PET/CT.
Tuan Vu1,2, Sophia R O'Brien1, Shawn X Ma1
1Department of Radiology, Hospital of the University of Pennsylvania, 3400 Spruce St, Philadelphia, PA 19147, USA.
Radiology Case Reports
|July 25, 2024
Summary
Pembrolizumab, an immune checkpoint inhibitor, can cause vasculitis. Fluorodeoxyglucose-positron emission tomography/computed tomography (FDG-PET/CT) identified vasculitis in an immunotherapy patient, which resolved with treatment.
Area of Science:
- Oncology
- Immunology
- Radiology
Background:
- Malignant pleural mesothelioma is a rare and aggressive cancer.
- Immune checkpoint inhibitors (ICIs) like pembrolizumab have revolutionized cancer treatment.
- ICIs can induce immune-related adverse events, including vasculitis.
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