Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Epidemiology and trace elements.

P C Elwood

    Clinics in Endocrinology and Metabolism
    |August 1, 1985
    PubMed
    Summary
    This summary is machine-generated.

    Epidemiology rigorously studies environmental trace elements and disease. While some links exist, like iodine and goiter, many associations, especially for cardiovascular disease and cancer, remain unclear or weak.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Air lead, blood lead and travel by car.

    Environmental geochemistry and health·2013
    Same author

    Evidence of a fall in cord blood lead levels in South Wales 1984-85.

    Environmental geochemistry and health·2013
    Same author

    Shear-induced Filter Blockage. A Population Based Appraisal of a Method for the Assessment of Platelet, White Cell and von Willebrand Factor Interactions.

    Platelets·2010
    Same author

    A Clinical Trial of Iron-fortified Bread.

    British medical journal·2010
    Same author

    Systematically missing confounders in individual participant data meta-analysis of observational cohort studies.

    Statistics in medicine·2009
    Same author

    Plasma fibrinogen level and the risk of major cardiovascular diseases and nonvascular mortality: an individual participant meta-analysis.

    JAMA·2005
    Same journal

    Long-term complications of diabetes.

    Clinics in endocrinology and metabolism·1986
    Same journal

    Diabetic retinopathy: current concepts of evaluation and treatment.

    Clinics in endocrinology and metabolism·1986
    Same journal

    Diabetic neuropathies and pain.

    Clinics in endocrinology and metabolism·1986
    Same journal

    The diabetic foot: pathophysiology and treatment.

    Clinics in endocrinology and metabolism·1986
    Same journal

    Autonomic neuropathy: its diagnosis and prognosis.

    Clinics in endocrinology and metabolism·1986
    Same journal

    Dialysis: continuous ambulatory peritoneal dialysis and haemodialysis.

    Clinics in endocrinology and metabolism·1986
    See all related articles

    Area of Science:

    • Environmental epidemiology
    • Public health research
    • Biostatistics

    Background:

    • Epidemiology is a precise science valuing reproducible measurements on representative samples.
    • Challenges include achieving high response rates, controlling confounding factors, and distinguishing causation from association.
    • Understanding epidemiological limitations is crucial for interpreting study conclusions.

    Purpose of the Study:

    • To review the role of environmental trace elements in human health.
    • To assess the strength of evidence linking trace elements to cardiovascular disease and cancer.
    • To highlight methodological challenges in environmental epidemiology.

    Main Methods:

    • Review of existing epidemiological studies on trace elements and disease.

    Related Experiment Videos

  • Analysis of known associations (e.g., iodine-goiter, fluoride-dental caries).
  • Discussion of confounding factors and limitations in trace element research.

    • Main Results:

    • Established links exist between specific trace elements and certain diseases.
    • Evidence for trace elements influencing cardiovascular disease is weak and likely not causal.
    • The role of trace elements in cancer is generally obscure, with few established causal links.

    Conclusions:

    • Strict adherence to epidemiological methods is essential for valid conclusions.
    • Many proposed trace element-disease associations require further investigation due to complexity and weak effects.
    • While some environmental factors impact health, the direct causal role of many trace elements in major diseases like cancer and cardiovascular disease is minimal.