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Updated: Jul 28, 2026

Murine Hind Limb Long Bone Dissection and Bone Marrow Isolation
Published on: April 14, 2016
Abstract:
This is a review of the chemistry and structure of synthetic, mineral, and biologic hydroxyapatites. Bone apatite has a large, reactive specific-surface and is characterized by its crystal imperfection and non-stoichiometry. Precipitated and bone hydroxyapatites are in the submicroscopic size range where their solubility decreases rapidly with a small increment of crystal growth. A discussion is given of the various mechanisms proposed for tissue mineralization. The body seems to contain a number of nucleating and inhibiting mechanisms which seem to work in concert, possibly providing redundant pathways to the mineralization of tissue.
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